Uses and Important Safety Information You Should Know About TRILIPIX¹

Uses for TRILIPIX® (fenofibric acid) delayed-release capsules

• Medicines to manage high cholesterol should only be used when diet and exercise alone have not been enough.

• TRILIPIX is used along with diet to lower triglycerides and raise HDL (good) cholesterol in people at high risk of heart disease who have abnormal cholesterol levels and are taking a statin medicine to manage LDL (bad) cholesterol.

• TRILIPIX is used along with diet to lower triglycerides and LDL cholesterol, and increase HDL cholesterol in people with abnormal cholesterol levels.

• TRILIPIX has not been shown to prevent heart attacks or stroke more than a statin alone.

Important Safety Information for TRILIPIX

• TRILIPIX should not be taken by people with liver, gallbladder, or severe kidney disease, nursing mothers, or those allergic to any product ingredient.

• Unexplained muscle pain, tenderness, or weakness may be a sign of a serious side effect and should be reported to your healthcare provider right away. Rarely, muscle-related problems can cause kidney damage and can be fatal. The risk of these side effects may be higher when TRILIPIX is used with a statin.

• Tell your healthcare provider about all the medicines you take.

• Your healthcare provider should do blood tests before and during treatment with TRILIPIX to check for liver problems. Some people may also require blood tests to check for kidney problems.

• TRILIPIX may cause inflammation (swelling) of the gallbladder or pancreas. Contact your healthcare provider if you experience abdominal pain, nausea, or vomiting.

• Women who are pregnant should not take statins. If you are pregnant or may become pregnant, talk with your healthcare provider about TRILIPIX.

• The most common side effects with TRILIPIX include headache, heartburn, nausea, muscle aches, and increases in muscle or liver enzymes that are measured by blood tests.

For more information, talk with your healthcare provider.